WebbSmall cell lung cancer (SCLC), the most lethal subtype of lung cancer (Oronsky et al., 2024), has a 5-year survival rate of less than 7% (Karachaliou et al., 2016) and accounts for approximately... Webb9 jan. 2024 · The combination of cis- or carboplatin and etoposide is the standard of care in the first-line treatment of stage IV (extensive-disease) SCLC (ED-SCLC). Despite …
Recent developments in limited stage small cell lung cancer
Webb13 maj 2024 · For decades, the standard of care for ES-SCLC was platinum and etoposide combination chemotherapy, with the incorporation of immune checkpoint blockade into frontline treatment only after 2024. 7, 8 There has been recent progress in recognizing distinct subtypes of SCLC using transcriptional profiling and multiple novel targeted … Webb11 aug. 2024 · Given the high propensity for small-cell lung cancer (SCLC) to develop brain metastases, prophylactic cranial irradiation (PCI) is a standard for care for patients with limited-stage SCLC and a therapeutic option for those with extensive-stage SCLC. 1, 2 Although meta-analyses and a prospective randomized trial have shown a survival … self-trust self-confidence
Treatment of extensive-stage small cell lung carcinoma: …
WebbRadiotherapy (RT) and chemotherapy continue to be widely utilized in small cell lung cancer (SCLC) management. In most limited stage (LS)-SCLC cases, the standard initial … Webb4 nov. 2024 · Background Small-cell lung cancer (SCLC) accounts for 12–15% of lung cancers and has a limited prognosis, with approximately one-third of SCLC patients … Webb21 maj 2024 · Small Cell Lung Cancer: Standard of Care. EP: 9. Extensive-Stage Small Cell Lung Cancer: Gaps in Treatment. EP: 10. Immunotherapy for First-Line Extensive-Stage … self-tuning-thread-pool-size-min