Phospho igf1r antibody
WebTarget description. This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. WebApr 11, 2024 · Prkaa1-T172D fl/fl phospho-mutant knock-in mice were generated by GemPharmatech (Nanjing, China) from embryonic stem cells (ESCs) modified via homologous recombination. To express phospho-mutant AMPKα1 specifically in MSCs, we crossed Prkaa1-T172D fl/fl mice with Prx1-Cre mice to generate conditionally AMPKα1 …
Phospho igf1r antibody
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WebIGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. WebIGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor.
WebMar 16, 2024 · The IGF-1R/PI-3K/Akt (IGF-1 receptor/Phosphatidyl Inositol-3 kinase/Akt) axis is considered an essential target for cervical cancer treatment 10 – 14. Several lines of evidence have suggested that O -GlcNAcylation may affect cancer cell proliferation/apoptosis by activating the PI-3K/Akt pathway 15 – 18. WebAnti-phospho-IGF1R (pTyr1165/pTyr1166) antibody produced in rabbit affinity isolated antibody Synonym (s): Anti-CD221 antibody produced in rabbit, Anti-IGFIR antibody produced in rabbit, Anti-JTK13 antibody produced in rabbit, Anti-MGC142170 antibody produced in rabbit, Anti-insulin-like growth factor 1 receptor antibody produced in rabbit
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WebIGF1R Rabbit Polyclonal Antibody -20ºC保存，Western一抗稀释液-20ºC或4ºC保存，一年有效。. Western一抗稀释液优先推荐4ºC保存，长期不使用可以考虑-20ºC保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。. 注意事项：. 如果本抗体用于Western blot (WB)、免疫 …
WebIGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines … suzhou s-win special fiber co. ltdWebIGF1R Phospho Antibody Array is a high-throughput ELISA based antibody array for qualitative protein phosphorylation profiling. It is suitable for comparing normal samples to treated or diseased samples, and identifying candidate biomarkers. suzhou talesun solar bistar tp7f72m 540 wWebFeb 24, 2024 · IGF-IRβ Antibody (F-1) is an IgG 2a κ mouse monoclonal IGF-IR beta antibody (also designated IGF1R antibody, CD221 antibody, or insulin like growth factor 1 receptor antibody) that detects the IGF-IR beta protein of mouse, rat and human origin by WB, IP, IF and ELISA. IGF-IRβ Antibody (F-1) is available as both the non-conjugated anti-IGF-IR beta … suzhou sweep electric appliance co. ltdWebRabbit polyclonal phospho-IGF1R (pTyr1165/pTyr1166) antibody. 100% Bioguaranteed. KR KO. 애플리케이션 제품 서비스 지원. All Photos (2) SAB4300069. Anti-phospho-IGF1R (pTyr 1165 /pTyr 1166) antibody produced in rabbit. affinity isolated antibody. All … skechers men\u0027s pull on bootsWebMar 21, 2024 · Function: Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. suzhou sweet fullhouseWebMar 16, 2024 · IGF1R phosphorylation was analysed by western blotting using an anti-phospho-IGF1R antibody. The blots were reprobed with an anti-IGF1R antibody (the uncropped western-blots are shown on... suzhou synta optical technologyWebMay 4, 2024 · IGF-1 Receptor α/IGF1R Antibody (1H7) is available as the non-conjugated anti-IGF-IRα antibody form, as well as multiple conjugated forms of anti-IGF-IRα antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor ® conjugates. suzhou sweep electric appliance