Phosphatase of regenerating liver-3
WebPRL-3, a cytokine-induced oncogenic phosphatase, is highly expressed in multiple myeloma cells and associated with poor outcome in this cancer. We studied whether PRL-3 … WebNational Center for Biotechnology Information
Phosphatase of regenerating liver-3
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OBJECTIVETo investigate the expression of phosphatase of regenerating liver-3 (PRL- 3) mRNA and evaluate its relationship with tumor invasion and metastasis in human … WebPhosphatase of Regenerating Liver-3 (PRL3) was discovered in 1998 and was subsequently found to be correlated with cancer progression and metastasis in 2001. Extensive research in the past two decades has produced significant findings on PRL3-mediated cancer signaling and functions, as well as its clinical relevance in diverse types of cancer.
WebNov 28, 2024 · Phosphatase of regenerating liver 3 (PRL-3), also known as PTP4A3, is a dual-specific, non-receptor PTP that is highly expressed in many tumors [ 6 ]. WebPhosphatase of regenerating liver-3 (PRL-3) has been shown to be involved in migration, invasion and metastasis in different types of cancer. 4-8 It maps to chromosome 8q24-3 and encodes a 22-kD protein tyrosine phosphatase with a carboxyl-terminal prenylation motif (CAAX). 9 Initially, PRL-3 was found to be overexpressed in liver metastases of …
WebNov 1, 2010 · Association of phosphatase of regenerating liver-3 (PRL-3) expression and clinical characteristics. Note: NS, not statistically significant. Moreover, there was no … WebFeb 10, 2024 · PRL-3, a cytokine-induced oncogenic phosphatase, is highly expressed in multiple myeloma cells and associated with poor outcome in this cancer. We studied whether PRL-3 influences metabolism. Cells transduced to express PRL-3 had higher aerobic glycolytic rate, oxidative phosphorylation, and ATP production than the control cells.
WebNov 1, 2016 · Although the phosphatase of regenerating liver-3 (PRL-3; also known as PTP4A3) is not found in most adult tissues, its overexpression is known to promote epithelial tumor progression, leading to poor outcome ( Guzińska-Ustymowicz and Pryczynicz, 2011; Rios et al., 2013 ).
WebPRL-3, a cytokine-induced oncogenic phosphatase, is highly expressed in multiple myeloma cells and associated with poor outcome in this cancer. We studied whether PRL … imdb edge of darknessWebNov 30, 2024 · Background Prostate cancer (PC) stratification needs new prognostic tools to reduce overtreatment. Phosphatase of regenerating liver (PRL-3) is a phosphatase … imed lsuWebDetects endogenous human, mouse and rat PRL-3 in Western blots. In Western blots, this antibody does not cross‑react with recombinant human PRL-1 or PRL‑2. Source Monoclonal Mouse IgG 2B Clone # 334402 Purification Protein A or G purified from hybridoma culture supernatant Immunogen E. coli -derived recombinant human PRL-3 Ala2-Met173 dutch emergency car packWebPhosphatase of regenerating liver-3 (PRL-3) has received attention as a molecule associated with metastasis in various tumor types, including gastric cancer. However, its … imdb synecdoche new yorkWebApr 15, 2024 · Phosphatase of regenerating liver-3 (PRL-3) is a member of the PRL family of intracellular dual-specificity protein tyrosine phosphatases [].PRL-3 localizes to the … imdb scum of the earthWebApr 6, 2024 · The liver is a vital organ with a unique regenerative capacity. Upon varying degrees of injury, the regenerating liver parenchymal cells are derived from pre-existing hepatocytes or biliary ... imdb the breakupWebDec 3, 2024 · Phosphatases of regenerating liver (PRL1–3) are among the most oncogenic protein phosphatases but their mechanism of action is poorly understood. Multiple substrates have been proposed as... dutch emergency number